We published a comprehensive review on the role of non-neuronal cells in ferroptosis and oxidative stress within the central nervous system. The article summarizes how glial cells, endothelial cells, and immune cells regulate ferroptotic vulnerability and contribute to neuroinflammation and neurodegeneration, highlighting novel therapeutic opportunities across neurological diseases. There is still much to explore in this emerging and exciting field!
(Figure 3 of the Review is displayed: https://doi.org/10.70401/fos.2026.0030)

In close collaboration with Pedro Rosa-Neto from the Translational Neuroimaging Laboratory, McGill University, and different groups from the Neurology department at the UKE, we carried out a meta-analysis on oral anticoagulation use in people treated with anti-amyloid therapies. Additionally, we conducted a study comparing different p-tau blood analytes in APOE4 carriers, the biggest risk fact for AD. Read the studies in JNNP or Alzheimer's & Dementia, respectively, a nice way to end 2025! We want to thank all collaborators and patients who make our research possible 🙏
JNNP: https://doi.org/10.1136/jnnp-2025-337386
A&D: https://doi.org/10.1002/alz.71048

Marcel received the Award of the Werner Otto Foundation in basic science for his work on the immunoproteasome in neurons. The award for clinical research went to Dr. Fatemeh Sadeghi, also from the neurology department, UKE. Find more details here: https://www.werner-otto-stiftung.de/foerderung-von-forschung/preis-der-werner-otto-stiftung/